USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: O14618 USC-OGP 2-DE database:  O14618 O14618 General information about the entry View entry in simple text format Entry name CCS_HUMAN Primary accession number O14618 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Copper chaperone for superoxide dismutase; AltName: Full=Superoxide dismutase copper chaperone;. Gene name Name=CCS Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0470: pI=5.11; Mw=31733 Cross-references UniProtKB/Swiss-Prot O14618; CCS_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CCS_HUMAN Primary accession number O14618 Secondary accession number(s) Q2M366 Q8NEV0 Sequence was last modified on  January 1, 1998 (version 1) Annotations were last modified on  March 15, 2017 (version 165) Name and origin of the protein Description RecName: Full=Copper chaperone for superoxide dismutase; AltName: Full=Superoxide dismutase copper chaperone; Gene name Name=CCS Encoded on Name=CCS Keywords 3D-structure; Chaperone; Complete proteome; Copper; Cytoplasm; Disulfide bond; Isopeptide bond; Metal-binding; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation; Zinc. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF002210; AAC51764.1; -; mRNA EMBL AY113179; AAM50090.1; -; mRNA EMBL CR541928; CAG46726.1; -; mRNA EMBL BC105016; AAI05017.1; -; mRNA EMBL BC112055; AAI12056.1; -; mRNA CCDS CCDS8146.1; -; . RefSeq NP_005116.1; NM_005125.1; . UniGene Hs.502917; -; . PDB 1DO5; X-ray; 2.75 A; A/B/C/D=84-237 PDB 2CRL; NMR; -; A=1-85 PDB 2RSQ; NMR; -; A=1-85 PDBsum 1DO5; -; . PDBsum 2CRL; -; . PDBsum 2RSQ; -; . ProteinModelPortal O14618; -; . SMR O14618; -; . BioGrid 115298; 15; . MINT MINT-153485; -; . STRING 9606.ENSP00000436318; -; . iPTMnet O14618; -; . PhosphoSitePlus O14618; -; . SwissPalm O14618; -; . BioMuta CCS; -; . OGP O14618; -; . EPD O14618; -; . MaxQB O14618; -; . PaxDb O14618; -; . PeptideAtlas O14618; -; . PRIDE O14618; -; . DNASU 9973; -; . Ensembl ENST00000533244; ENSP00000436318; ENSG00000173992; . GeneID 9973; -; . KEGG hsa:9973; -; . UCSC uc001oir.4; human; . CTD 9973; -; . DisGeNET 9973; -; . GeneCards CCS; -; . HGNC HGNC:1613; CCS; . HPA CAB008672; -; . HPA HPA040026; -; . HPA HPA044090; -; . MIM 603864; gene; . neXtProt NX_O14618; -; . OpenTargets ENSG00000173992; -; . PharmGKB PA26177; -; . eggNOG ENOG410IPMW; Eukaryota; . eggNOG COG2032; LUCA; . GeneTree ENSGT00530000063226; -; . HOGENOM HOG000263450; -; . HOVERGEN HBG018933; -; . InParanoid O14618; -; . KO K04569; -; . OMA DNDKMVC; -; . OrthoDB EOG091G0FQ1; -; . PhylomeDB O14618; -; . TreeFam TF105184; -; . Reactome R-HSA-3299685; Detoxification of Reactive Oxygen Species; . EvolutionaryTrace O14618; -; . GeneWiki CCS_(gene); -; . GenomeRNAi 9973; -; . PRO PR:O14618; -; . Proteomes UP000005640; Chromosome 11; . Bgee ENSG00000173992; -; . CleanEx HS_CCS; -; . ExpressionAtlas O14618; baseline and differential; . Genevisible O14618; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0005507; F:copper ion binding; IDA:GO_Central; . GO GO:0015035; F:protein disulfide oxidoreductase activity; TAS:Reactome; . GO GO:0004784; F:superoxide dismutase activity; IBA:GO_Central; . GO GO:0008270; F:zinc ion binding; IBA:GO_Central; . GO GO:0015680; P:intracellular copper ion transport; TAS:ProtInc; . GO GO:0051353; P:positive regulation of oxidoreductase activity; IEA:Ensembl; . GO GO:0019430; P:removal of superoxide radicals; IBA:GO_Central; . GO GO:0000302; P:response to reactive oxygen species; TAS:Reactome; . GO GO:0006801; P:superoxide metabolic process; TAS:ProtInc; . CDD cd00305; Cu-Zn_Superoxide_Dismutase; 1; . CDD cd00371; HMA; 1; . Gene3D 2.60.40.200; -; 1; . InterPro IPR006121; HMA_dom; . InterPro IPR018152; SOD_Cu/Zn_BS; . InterPro IPR001424; SOD_Cu_Zn_dom; . Pfam PF00403; HMA; 1; . Pfam PF00080; Sod_Cu; 1; . PRINTS PR00068; CUZNDISMTASE; . SUPFAM SSF49329; SSF49329; 1; . SUPFAM SSF55008; SSF55008; 1; . PROSITE PS50846; HMA_2; 1; . PROSITE PS00332; SOD_CU_ZN_2; 1; .

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